Concomitant therapy with cobicistat-containing regimen – no dose adjustment is needed; the dose of Paxlovid is 300 mg/100 mg twice daily for 5 days. Patients diagnosed with human immunodeficiency virus (HIV) who are receiving cobicistat-containing regimen should continue their treatment as indicated.

No dose adjustment of Paxlovid is needed. Patients diagnosed with human immunodeficiency virus (HIV) infection who are receiving a cobicistat-containing regimen should continue their treatment as indicated.

Patients on cobicistat-containing HIV regimens should continue their treatment as indicated. Coadministration may increase darunavir concentrations. For further information, refer to the darunavir/cobicistat prescribing information. Monitor for increased Paxlovid or protease inhibitor adverse events.